Publication
Publisher:
Annals Of Neuroscience, 2015; 22(1):31-36. PubMed PMID: 26124548
Publication Type:
Journal
Publication Title:
Hippocampal And Striatal Histomorphology Following Chronic Nicotine Administration In Female And Male Rats
Publication Authors:
Ijomone OM, Olaibi OK, Esomonu UG, Nwoha PU
Year Published:
2015
Abstract:
Publisher:
Pathophysiology, 2015; 22(1): 57-63. PubMed PMID: 25601213.
Publication Type:
Journal
Publication Title:
Chronic Nicotine Administration Does Not Alter Cognitive Or Mood Associated Behavioural Parameters
Publication Authors:
Ijomone OM, Olaibi OK, Biose IJ, Mba C, Tete SA, Nwoha PU
Year Published:
2015
Abstract:
Publisher:
Obafemi Awolowo University, Ile-Ife, Nigeria
Publication Type:
Disertations
Publication Title:
A Study Of The Effects Of Nicotine On Hippocampal And Striatal Histomorphology, Neurogenesis And Neurobehaviour In Adult Male Wistar Rats
Publication Authors:
Ijomone OM
Year Published:
2015
Abstract:
NILL
Publisher:
Journal Of Experimental And Clinical Anatomy, 2014; 13(1): 12-16
Publication Type:
Journal
Publication Title:
Histomorphometric Study Of Stomach And Duodenum Of Aspirin Treated Wistar Rats
Publication Authors:
Olaibi OK, Ijomone OM, Ajibade AJ.
Year Published:
2014
Abstract:
Publisher:
Pathophysiology, 2014; 21:185-190. PubMed PMID: 25159662.
Publication Type:
Journal
Publication Title:
Effects Of Chronic Nicotine Administration On Body Weight, Food Intake And Nitric Oxide Concentration In Female And Male Rats
Publication Authors:
Ijomone OM, Olaibi OK, Nwoha PU
Year Published:
2014
Abstract:
Publisher:
Annals Of Bioanthropology, 2014; 2(1):13-16.
Publication Type:
Journal
Publication Title:
Anthropometric Analysis Of The Nose Of The Ejagham Ethnic Group In Cross River State, Nigeria
Publication Authors:
Esomonu UG, Ijomone OM, Ude RA, Nandi EM
Year Published:
2014
Abstract:
Publisher:
Annals Of Neuroscience;2014; 21(2): 42-46. PubMed PMID: 25206059.
Publication Type:
Journal
Publication Title:
Performance On Motor Associated Behavioural Tests Following Chronic Nicotine Administration
Publication Authors:
Ijomone OM, Olaibi OK, Biose IJ, Mba C, Umoren KE, Nwoha PU
Year Published:
2014
Abstract:
Publisher:
Journal Of Experimental And Integrative Medicine, 2014; 4(2):123-130.
Publication Type:
Journal
Publication Title:
Mucus Secreting Activity And Nitric Oxide Concentrations Of Ethanol-injured Pylorus And Duodenum Of Wistar Rats Pre-treated With Moringa Oleifera
Publication Authors:
14. Olaibi OK, Ijomone OM, Olawuni IJ, Adewole SO, Akinsomisoye SO
Year Published:
2014
Abstract:
Publisher:
Al Ameen Journal Of Medical Sciences, 2014; 7(2):104-111.
Publication Type:
Journal
Publication Title:
Histological And Histomorphometric Studies Of Ethanol-injured Pylorus And Duodenum Of Wistar Rats Pre-treated With Moringa Oliefera Extract
Publication Authors:
Olaibi OK, Ijomone OM, Adewole SO
Year Published:
2014
Abstract:
Publisher:
European Journal Of Medicinal Plants, 2014; 4(3): 353-464.
Publication Type:
Journal
Publication Title:
Hypoglycemic And Hypolipidemic Activities Of Methanolic Extract Of Sphenocentrum Jollyanum On Streptozotocin-Induced Diabetic Wistar Rats
Publication Authors:
Alese MO, Adewole OS, Ijomone OM, Ajayi SA, Alese OO
Year Published:
2014
Abstract:
Aims: This study is to provide scientific basis for the folkloric use of Sphenocentrum
jollyannum roots in the management and/control of Diabetes mellitus. The effects of the
extract on blood glucose level and serum lipid profile in Streptozotocin-induced diabetic
rats was investigated. The efficacy was also compared with that of glibenclamide, a
known antidiabetic drug.
Study Design: Experimental Study.
Place and Duration of Study: Department of Anatomy and Cell Biology, Obafemi
Awolowo University, Ile-Ife, Nigeria and Department of Chemical Pathology, Ekiti State
University Teaching Hospital, Ado Ekiti, Nigeria, between November, 2010 and April,
2012.
Methodology: Twenty four adult Wistar rats were randomly divided into four groups (A, B, C and D) of six rats each and used for this research. Diabetes mellitus was induced in
groups B, C and D by a single intraperitoneal injection of streptozotocin (80mg/kg body
weight) dissolved in 0.1 M citrate buffer. Group A, the control rats were intraperitoneally
injected with an equivalent volume of citrate buffer. Group B diabetic rats were untreated
while groups C and D received Methanolic extract of Sphenocentrum jollyanum (MESJ)
(200mg/kg) and glibenclamide (0.5mg/kg) once daily for two weeks respectively.
Results: The result showed a significant (P < 0.05) fall in blood glucose and serum lipid
levels with MESJ and glibenclamide administration. A significant (P < 0.05) decrease in
the raise of lipids in serum and improvement in the lipid levels to an almost normal
condition was also observed.
Conclusion: Sphenocentrum jollyanum roots possess hypoglycemic and hypolipidemic
effects on diabetic rats lending credence to its use in the traditional management and/or
control of Diabetes mellitus.